In recent years, photobiomodulation (PBM) has become increasingly relevant in the veterinary field, demonstrating significant benefits in healing skin wounds as well. However, so far its use in birds has been poorly documented. New research has tested for the first time the efficacy of the patented Multiwave Locked System (MLS®) technology, using the M-VET device in the treatment of skin wounds in three bird species: a peregrine falcon (Falco peregrinus), a little owl (Tyto alba) and a Rosy-faced Lovebird (Agapornis roseicollis).
The results? Very promising. The MLS® laser has proved to be an effective and non-invasive therapeutic option, accelerating wound healing and improving patient well-being.
What is Photobiomodulation and How Does It Work?
Photobiomodulation (PBM) is a therapy that uses light in the red and near infrared (NIR) range to stimulate biological processes in cells. This mechanism is based on the absorption of light by the mitochondrial cytochrome c oxidase, promoting:
- The production of ATP, cellular energy
- The modulation of oxidative stress
- An increase in the synthesis of growth factors
- An anti-inflammatory and regenerative action
In the case of birds, the very thin dermis and particular physiology require adapted treatment parameters, with specific dosages and intensities.
The study: three success stories with the MLS® laser
Case 1: Peregrine Falcon
A young peregrine falcon presented with chronic skin wounds on its legs, probably caused by inadequate equipment (too large jesses and closed ring). After topical and antibiotic treatments with limited improvement, MLS® Laser Therapy with M-VET was introduced (used in all three cases):
- 3 sessions every 72 hours during the first week with the “contaminated wound” protocol
- 2 sessions every 72 hours during the second week with the “contaminated wound” protocol
- 1 final session after 96 hours with the “wound” protocol
Result: Healing was accelerated, with complete resolution of the milder lesion and a marked improvement of the more severe one, which closed completely a few days after the end of treatment.
Case 2: Little Owl
A little owl presented with a wound to the right tarsal-metatarsal joint, which developed after a jess was applied. Despite treatments with meloxicam and disinfectants, the lesion persisted.
Result: After treatment with MLS®, the wound showed a clear improvement already after the first week, with a reduction in ulceration and purulent secretion. After the sixth session, the skin was completely healed.
Case 3: Rosy-faced Lovebird
A rosy-faced lovebird suffered from feather pecking and chronic skin lesions on the right shoulder and wing. Various topical treatments and antibiotics had led to modest results.
Result: After one week of MLS®, the lesion on the wing showed significant improvements. By the sixth session, the skin was completely regenerated.
Why is the MLS® Laser revolutionary?
Use of MLS® technology through the M-VET device has shown:
✔ Reduction of inflammation thanks to the modulation of pro-inflammatory cytokines (IL-1β, IL-18)
✔ Increased cellular metabolism, stimulating tissue repair
✔ Improved extracellular matrix turnover, essential for skin repair
✔ High tolerability in birds, with no noted side effects
Conclusions
This research represents a turning point in avian medicine: MLS® Laser Therapy could become a standard therapy for the treatment of wounds in birds, reducing healing times and improving animal well-being.
Next steps? Larger studies to confirm the observed benefits and to refine the treatment protocols.
Use of Multiwave Locked System (MLS®) as an Adjuvant Therapy for the Management of Skin Wound Healing in Birds: A Case Series
V. Gismondi, F. Gesuete, L. Crosta, G. Zanna
Anicura-Istituto Veterinario di Novara
Journal of Zoological Research | Volume 7, Issue 1, 2025